Serum & Plasma

iBioSpecimen offers customized access to high-quality human whole blood samples for research, diagnostic development, pharmaceutical studies, biomarker programs, genomics, immunology, liquid biopsy development, and clinical assay validation. We support researchers, diagnostic companies, CROs, pharmaceutical companies, biotechnology firms, academic institutions, and medical device developers looking for human whole blood samples in the USA, UK, Europe, Asia, and other international regions. Our whole blood sourcing service is designed for organizations that require reliable human blood specimens from healthy donors, disease-state donors, and study-specific patient populations.

Through our global biospecimen sourcing network, iBioSpecimen helps research teams obtain fresh human whole blood samples, healthy donor whole blood, diseased donor whole blood, residual clinical blood samples, banked whole blood specimens, and prospectively collected whole blood samples based on defined scientific, clinical, logistical, and pre-analytical requirements. Whether your organization is based in the United States, United Kingdom, Europe, or another international market, we can help source whole blood samples aligned with your research protocol and project timeline.

Human whole blood is a highly valuable biospecimen because it represents a complete circulating biological system. Unlike isolated serum or plasma, whole blood contains cellular and non-cellular components, including red blood cells, white blood cells, platelets, plasma, immune cells, nucleic acids, proteins, metabolites, inflammatory markers, and disease-associated molecular signals. This makes human whole blood especially useful for studies where researchers need to evaluate immune response, genetic information, cellular composition, blood-based biomarkers, disease progression, therapeutic response, or diagnostic assay performance.

At iBioSpecimen, each human whole blood sample procurement project can be reviewed according to donor profile, disease indication, blood volume, collection tube, anticoagulant, processing window, storage temperature, shipping condition, country preference, and available clinical information. Clients may request whole blood samples from healthy donors or patients with specific medical conditions, including oncology, infectious diseases, autoimmune disorders, inflammatory diseases, cardiovascular diseases, metabolic disorders, neurological conditions, respiratory diseases, liver disease, kidney disease, rare diseases, and other clinical indications.

Our human whole blood samples for research support a wide range of scientific and commercial applications. Researchers use whole blood for DNA extraction, RNA analysis, PCR assay development, next-generation sequencing, pharmacogenomics, inherited disease studies, infectious disease testing, immune profiling, cytokine research, liquid biopsy workflows, hematology research, companion diagnostic development, IVD assay validation, and medical device testing. Whole blood samples are also useful for assay optimization, reagent evaluation, platform comparison, analytical sensitivity studies, and method development.

For genomics and molecular diagnostics, whole blood is one of the most commonly used sample types because it provides a stable and rich source of genomic DNA and cellular material. Diagnostic manufacturers, clinical laboratories, and molecular assay developers in the USA, UK, and Europe may require EDTA whole blood or other defined collection formats to develop, verify, or validate PCR-based assays, NGS panels, genetic screening tests, pharmacogenomic workflows, and molecular diagnostic platforms. iBioSpecimen can help source blood samples based on required donor characteristics, collection conditions, and downstream molecular testing needs.

For oncology and liquid biopsy research, whole blood can support the study of circulating biomarkers, immune response, tumor-associated molecular changes, treatment monitoring, and cancer-related blood signatures. Depending on availability, iBioSpecimen can assist with sourcing oncology whole blood samples from patients with specific cancer indications, disease stages, treatment histories, or matched biospecimen requirements. Oncology whole blood samples may also be paired with plasma, serum, buffy coat, FFPE tissue blocks, fresh frozen tissue, or de-identified clinical data to support deeper translational research and multi-omics analysis.

For infectious disease and immune response studies, whole blood samples are useful for understanding host-pathogen interactions, inflammatory pathways, antibody response, immune cell activity, and molecular detection performance. Researchers may request whole blood from donors with defined infectious disease status, clinical history, laboratory test results, or time-sensitive collection requirements. These samples can support assay development for molecular diagnostics, serology platforms, antigen testing, immune monitoring, and research-use infectious disease panels.

For autoimmune, inflammatory, and chronic disease research, disease-state whole blood samples can help researchers study immune dysregulation, cytokine activity, cellular signatures, inflammation markers, autoantibody-related pathways, and disease-associated biomarkers. iBioSpecimen can assist with whole blood procurement from patient groups with selected clinical conditions when available, helping research teams compare healthy and diseased donor profiles for discovery, validation, and translational research programs.

iBioSpecimen can support whole blood collection in different tube types and anticoagulant formats based on the intended application. Common options may include EDTA whole blood samples, sodium heparin whole blood, lithium heparin whole blood, sodium citrate whole blood, and other protocol-defined collection formats. EDTA whole blood is frequently requested for molecular testing and genomic applications, while heparinized whole blood may be preferred for certain cell-based or immunology workflows. Citrated whole blood may be required for coagulation, platelet, and hematology-related studies. Our sourcing process helps align the collection method with the scientific use of the sample.

We also support requests for matched whole blood and biospecimen sets, which are valuable when researchers need multiple sample types from the same donor. Matched sets may include whole blood with plasma, serum, buffy coat, PBMCs, FFPE tissue, fresh frozen tissue, urine, saliva, or clinical annotations. These paired samples can help support liquid biopsy correlation, tumor-normal comparison, biomarker validation, pharmacogenomics, multi-omics research, and patient-level disease profiling.

For study-specific requirements, iBioSpecimen can help coordinate prospective whole blood collection programs across suitable collection sites and partner networks. Prospective collection is useful when researchers need fresh samples, defined donor inclusion and exclusion criteria, controlled collection timing, specific tube types, special processing conditions, or shipment within a defined time window. This approach is especially helpful for projects where sample freshness, donor selection, and pre-analytical consistency are critical to the success of the study.

Our whole blood sourcing process is built around ethical access, sample traceability, donor privacy, and research-use documentation. Depending on the source, project scope, and consent permissions, samples may be supported with de-identified donor demographics, diagnosis information, collection date, tube type, anticoagulant, processing details, storage conditions, laboratory values, and other available clinical annotations. This level of sample information helps clients select blood specimens with greater confidence and improves the usability of the samples for research and development.

iBioSpecimen serves pharmaceutical companies, biotechnology firms, CROs, diagnostic manufacturers, academic research groups, clinical research organizations, and medical device developers in the United States, United Kingdom, Europe, Asia, and worldwide. Whether your organization is building a new diagnostic assay, validating a molecular workflow, conducting biomarker discovery, supporting an immunology program, developing a liquid biopsy platform, or sourcing disease-state blood for translational research, our team can help identify suitable sample options through our global network.

With flexible sourcing capabilities and access to diverse donor populations, iBioSpecimen helps reduce the complexity of human whole blood procurement. We support small pilot requests, custom sample searches, matched biospecimen projects, and larger multi-site blood collection programs. Our goal is to provide research teams with the right whole blood specimens, collected and delivered according to project-specific requirements.

If your organization is looking for human whole blood samples for research in the USA, UK, Europe, or worldwide, iBioSpecimen can help source healthy donor blood, disease-state whole blood, fresh whole blood, residual clinical blood, banked specimens, matched sample sets, and custom prospective collections. Share your required sample type, disease indication, donor criteria, blood volume, anticoagulant preference, processing timeline, clinical data needs, country preference, and shipping destination, and our team will review suitable sourcing options for your research or development program.

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Obtaining the correct serum or plasma sample can be challenging when a study requires specific donor demographics, disease conditions, infection status, collection tubes, anticoagulants, processing methods, storage conditions, or clinical data. iBioSpecimen simplifies this process by connecting researchers with a global network of hospitals, laboratories, blood centers, clinics, biobanks, and research partners.

Our sourcing network enables access to a broad and diverse range of donor populations, including healthy individuals, patients with diagnosed medical conditions, and donors with specific clinical histories. This allows researchers to target different patient profiles and obtain samples that match their study design.

We can assist with sourcing serum and plasma samples from the United States, Europe, Asia, and other international regions. Whether your project requires a small number of samples for pilot testing or a large cohort for assay validation, iBioSpecimen can help identify suitable availability through our global sample provider network.

iBioSpecimen can help source a wide variety of serum and plasma samples depending on your research needs. These may include:

Normal human serum samples from healthy donors for control studies, assay development, reference testing, biomarker comparison, and method validation.

Disease-state serum samples from patients diagnosed with specific diseases for biomarker discovery, diagnostic assay development, drug development, and clinical research.

Normal human plasma samples from healthy donors collected using defined anticoagulants and processing conditions.

Disease-state plasma samples from patients with oncology, infectious disease, autoimmune, inflammatory, cardiovascular, metabolic, neurological, and other clinical conditions.

Residual clinical serum and plasma samples obtained from leftover clinical specimens where ethically permitted and suitable for research use.

Pooled serum and pooled plasma samples for assay controls, method development, quality control, and large-volume research applications.

Single-spin and double-spin plasma samples for applications requiring specific processing conditions, including liquid biopsy, cfDNA research, molecular diagnostics, and biomarker studies.

Prospectively collected serum and plasma samples based on custom donor criteria, disease indication, collection protocol, processing timeline, storage condition, and shipping requirements.

Human serum is the liquid portion of blood collected after clotting and removal of blood cells and clotting factors. It is commonly used in clinical research, immunology, serology, biomarker discovery, infectious disease studies, therapeutic monitoring, and diagnostic assay development.

iBioSpecimen can assist with sourcing healthy donor serum, disease-specific serum, residual clinical serum, pooled serum, and prospectively collected serum samples. These samples may be used for antibody testing, cytokine analysis, protein biomarker research, hormone studies, drug response research, serological assay development, and diagnostic validation.

Researchers may request serum samples according to donor age, gender, ethnicity, diagnosis, disease stage, treatment history, infection status, collection date, storage condition, sample volume, and available de-identified clinical data.

Human plasma is the liquid component of blood collected with anticoagulants, containing proteins, clotting factors, circulating nucleic acids, metabolites, antibodies, and other biomarkers. Plasma samples are widely used in molecular diagnostics, liquid biopsy studies, oncology research, pharmacokinetics, infectious disease testing, biomarker discovery, and IVD assay development.

iBioSpecimen can support procurement of normal human plasma, disease-state plasma, EDTA plasma, heparin plasma, sodium citrate plasma, single-spin plasma, double-spin plasma, frozen plasma, residual clinical plasma, and pooled plasma samples.

Plasma samples may be especially useful for studies involving circulating tumor DNA, circulating free DNA, RNA biomarkers, inflammatory markers, coagulation studies, infectious disease biomarkers, immune response analysis, and drug development programs.

iBioSpecimen supports access to disease-state serum and plasma samples from patients with a wide range of medical conditions. Depending on project requirements and sample availability, these may include:

Oncology serum and plasma samples, including samples from patients with lung cancer, breast cancer, colorectal cancer, prostate cancer, liver cancer, pancreatic cancer, ovarian cancer, gastric cancer, hematological malignancies, and other tumor types.

Infectious disease serum and plasma samples, including specimens tested for specific infections, antibodies, antigens, or molecular markers.

Autoimmune disease serum and plasma samples for research involving immune response, autoantibodies, inflammation, cytokines, and disease-associated biomarkers.

Cardiovascular disease serum and plasma samples for studies involving heart disease, vascular conditions, coagulation markers, lipid markers, inflammation, and metabolic risk factors.

Metabolic disease serum and plasma samples, including samples from patients with diabetes, obesity, liver disease, kidney disease, endocrine disorders, and related conditions.

Neurological disease serum and plasma samples for biomarker discovery, neuroinflammation studies, degenerative disease research, and diagnostic development.

These disease-state samples can help researchers compare healthy and diseased donor profiles, discover new biomarkers, validate diagnostic assays, and support translational research programs.

iBioSpecimen can assist with access to residual clinical serum and plasma samples where available and ethically permitted. Residual samples may be useful for research projects requiring real-world clinical specimens, specific disease indications, infection-tested samples, or samples with laboratory data.

We can also help source pooled serum and plasma samples for applications such as assay development, assay controls, reagent testing, method optimization, quality control, and diagnostic manufacturing support. Pooled samples may be requested from healthy donors or selected donor groups depending on study needs.

For certain research programs, clients may require serum or plasma samples that have been tested for specific infections, analytes, antibodies, antigens, chemicals, drugs, or clinical markers. iBioSpecimen can help identify availability for tested residual clinical samples or custom collections based on required testing criteria.

These samples may support infectious disease assay development, serology testing, toxicology studies, diagnostic validation, biomarker research, and medical device performance evaluation.

When banked samples are not sufficient, iBioSpecimen can support prospective serum and plasma collection through its global provider network. Prospective collection may be suitable when your study requires specific donor criteria, disease conditions, collection tubes, anticoagulants, processing time, spin protocol, storage temperature, sample volume, or clinical documentation.

Custom collection options may include healthy donor serum, disease-state serum, EDTA plasma, heparin plasma, sodium citrate plasma, single-spin plasma, double-spin plasma, fasting samples, non-fasting samples, matched blood and tissue samples, and longitudinal sample collection.

Prospective sourcing is especially valuable for studies requiring defined collection protocols, fresh sample processing, rare disease indications, matched sample sets, or controlled pre-analytical conditions.

Where available, serum and plasma samples may be provided with de-identified clinical data and donor information. The level of data depends on sample type, collection site, consent permissions, and study requirements.

Available information may include donor age, gender, ethnicity, diagnosis, disease stage, treatment history, medication history, laboratory values, infection status, collection date, sample processing details, storage condition, and other relevant clinical annotations.

Annotated serum and plasma samples are highly valuable for biomarker discovery, assay validation, companion diagnostic development, patient stratification research, and translational medicine programs.

Human serum and plasma samples are widely used across many research and development areas, including:

Biomarker discovery and validation
Molecular diagnostics
Liquid biopsy research
IVD assay development
Serology assay development
Immunology research
Infectious disease studies
Oncology research
Autoimmune disease research
Drug discovery and development
Pharmacokinetic and pharmacodynamic studies
Protein and cytokine analysis
Hormone and metabolic studies
Medical device validation
Clinical research and translational medicine
Companion diagnostic development
Genomics and proteomics research

By providing access to both normal and disease-state serum and plasma specimens, iBioSpecimen helps researchers build stronger study cohorts and generate more meaningful scientific data.

At iBioSpecimen, we understand that sample quality, ethical sourcing, and traceability are critical for successful research. We focus on connecting researchers with reliable serum and plasma samples collected through established clinical and research networks.

Our sourcing process is designed to support protocol-based collection, donor diversity, sample documentation, proper handling, storage integrity, and timely delivery. Whether your organization requires residual samples, banked specimens, pooled samples, or prospective collections, iBioSpecimen helps coordinate sourcing according to your research needs.

If your organization is looking for high-quality human serum and plasma samples for research, iBioSpecimen can help identify suitable options based on your project requirements. Share your required sample type, disease indication, donor criteria, sample volume, anticoagulant preference, processing method, clinical data needs, and shipping destination, and our team will review availability through our global biospecimen sourcing network.

iBioSpecimen supports pharmaceutical companies, biotech firms, CROs, diagnostic manufacturers, academic researchers, and medical device companies with reliable access to normal and disease-state serum and plasma samples for research, diagnostics, and development programs.